2025; Immunity:
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
2024, Cell Death & Differentiation:
Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice
2024, Cell Reports:
Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.
2024, Nature Metabolism:
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function
2023, Nature Immunology:
Mitochondrial damage activates the NLRP10 inflammasome
2019, Nature Communications:
Alternative splicing regulates stochastic NLRP3 activity.
2018, Immunity:
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
2017, The Journal of Experimental Medicine:
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain.
2015, Journal of Immunology:
ATF3 Is a Key Regulator of Macrophage IFN Responses.
2014, Journal of Immunology:
The UNC93B1 Tyrosine-Based Motif Regulates Trafficking and TLR Responses via Separate Mechanisms.
2014, Journal of Leukocyte Biology:
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
2002, PNAS:
T-DNA integration into the barley genome from single and double cassette vectors.
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